For anti-aging, general health & healing, fat mobilization. For these purposes, a dose of 2-3 IU’s per day will be sufficient for the majority. A dose of 1.5 to 2.0 IU’s is considered to be a full replacement dose for those in their middle-age and beyond. For gaining lean muscle and substantially improving body composition. For this purpose a dose of 4-8 IU’s per day will be necessary. Most people will respond very well at a dose of 4-5 IU's per day.